For the sixth straight week Augustana (40-4) has kept the top spot in the NFCA Division II Top 25 Coaches Poll. The Vikings received all 16 first-place votes.
| Rank | School | Points | 2021 Record | Last Poll |
| 1 | Augustana (16) | 400 | 40-4 | 1 |
| 2 | North Georgia | 380 | 36-5 | 3 |
| 3 | Auburn Montgomery | 361 | 39-5 | 4 |
| 4 | Oklahoma Christian | 354 | 36-6 | 6 |
| 5 | Lincoln Memorial | 327 | 36-6 | 5 |
| 6 | UT Tyler | 313 | 33-7 | 2 |
| 7 | Indianapolis | 311 | 43-6 | 7 |
| 8 | Young Harris | 273 | 31-9 | 10 |
| 9 | Valdosta State | 268 | 34-8 | 8 |
| 10 | Texas A&M-Commerce | 260 | 28-15 | 12 |
| 11 | Concordia Irvine | 246 | 26-11 | 11 |
| 12 | West Texas A&M | 220 | 32-10 | 9 |
| 13 | Grand Valley State | 209 | 37-7 | 13 |
| 14 | Central Oklahoma | 191 | 34-10 | 15 |
| 15 | Colorado Mesa | 163 | 34-2 | 16 |
| 16 | UAH | 153 | 31-12 | 14 |
| 17 | Minnesota State | 150 | 34-7 | 17 |
| 18 | Saint Anselm | 147 | 27-4 | 18 |
| 19 | Southern Arkansas | 103 | 26-7 | 22 |
| 20 | Angelo State | 80 | 31-11 | 21 |
| 21 | Rollins | 75 | 19-2 | 23 |
| 22 | Georgian Court | 63 | 33-4 | 24 |
| 23 | Winona State | 56 | 33-10 | 20 |
| 24 | Biola | 35 | 19-13 | 25 |
| 25 | Kutztown | 24 | 31-11 | RV |
New to Poll: No. 25 Kutztown
Dropped Out: No. 19 West Florida
Receiving Votes: Tampa (14), Northwest Nazarene (12), Central Missouri (4), Texas A&M University-Kingsville (4), West Florida (2), Rogers State (1), West Liberty (1).